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MAPK-regulated expression of the gut protein ALP2 facilitates Apolygus lucorum susceptibility to Mpp51Aa toxins
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DOI：10.1016/j.ecoenv.2026.120640.png)
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Abstract
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• Mpp51Aa1 and Mpp51Aa2 elicit distinct, time-dependent transcriptomic responses in A. lucorum. • p38 and ERK pathways facilitate Mpp51Aa-induced damage in the insect midgut. • ALP2 is identified as an essential susceptibility factor for Mpp51Aa toxins. • MAPK activation trans-regulates the expression of ALP2.
Keywords:
Apolygus lucorum
Mpp51Aa toxins
MAPK signaling
ALP2
Transcriptomics
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