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Maternal hyperhomocysteinemia compromises female offspring fertility through overactivation of primordial follicles

delete2026-06-19
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OA
AI
J
Jinmei Gao
L
Lu Wang
J
Jie Ma
J
Jialing Li
Y
Yajie Wang
J
Jinfang Wang
R
Rong Hu *
DOI：10.1016/j.isci.2026.116393delete
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Abstract

Abstract

En 中文
• Maternal HHcy adversely affects reproductive health in female offspring • Maternal HHcy overactivates prepubertal primordial follicles, depleting ovarian reserve early • Maternal HHcy impairs oocyte quality in offspring
Keywords:
molecular biology
female reproductive endocrinology
developmental biology

Journal

iScience cover
iScience
IF:
4.1
Papers:
4.6K
Citations:
4.1W

Organization

N
ningxia medical university
Scholars:
1.5K
Papers: 437
Citations: 0
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