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Mechanical signature of cancer cells: From cytoskeletal alterations to cell rheology

delete2026-05-14
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PRE
AI
I
Ibrahim Ghoytasi *
M
Mahsa Salehi
A
Alireza Fotouhi
R
Reza Babakhani Galangashi
M
Mahdieh Hashemi
A
Ali Zarrabi *
M
Massoud Vosough *
DOI:10.1016/j.pbiomolbio.2026.05.001delete
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Abstract

Abstract

En 中文
• Cytoskeletal remodeling links EMT to cancer cell mechanical phenotypes. • Quantifies elasticity and viscoelasticity using AFM, tweezers, and microfluidics. • Compares rheological models (power-law, SLS, Maxwell) for parameter extraction. • Summarizes benchmark values across methods in tables and supplementary data. • Outlines standardization needs to translate mechanical signatures into biomarkers.
Keywords:
cytoskeletal remodeling
cancer cell mechanics
rheological modeling
atomic force microscopy
viscoelasticity

Journal

Progress in Biophysics and Molecular Biology cover
Progress in Biophysics and Molecular Biology
IF:
4.5
Papers:
1.8K
Citations:
4.7K

Organization

A
ACECR
Scholars:
312
Papers: 151
Citations: 30
P
Purdue University
Scholars:
2.6W
Papers: 2.0W
Citations: 147
I
istinye university
Scholars:
297
Papers: 212
Citations: 0
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