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Medial Geniculate Body Deep Brain Stimulation for Refractory Tinnitus: Neurophysiological Rationale and Translational Neuromodulation Perspectives
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DOI:10.1016/j.neurom.2026.06.476.png)
Abstract
En 中文
Chronic tinnitus imposes considerable functional and socioeconomic burden, particularly in patients with treatment-refractory disease despite available therapies. Increasing evidence supports tinnitus as a disorder of maladaptive brain network activity rather than solely peripheral pathology, motivating circuit-based neuromodulatory interventions. This review synthesizes the neurophysiological rationale and translational evidence for deep brain stimulation (DBS) of the medial geniculate body (MGB) as a therapeutic strategy for refractory tinnitus.
Keywords:
deep brain stimulation
medial geniculate body
tinnitus
neuromodulation
thalamocortical dysrhythmia
sensory gating
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