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Mediation effect of depression and health-promoting lifestyle between social isolation and frailty in elderly patients with colorectal cancer in China: A cross-sectional study
10.1016/j.ejon.2026.103109
2026-01-22
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Abstract
En 中文
• The incidence of frailty among elderly colorectal cancer patients is high, with nearly half of the patients already experiencing frailty. • Social isolation directly predicts frailty through the mediating effects of depression and health-promoting lifestyles, and indirectly predicts frailty through the chain mediation of depression and health-promoting lifestyles. • This study emphasizes the importance of addressing social isolation, as well as improving depression management and health-promoting lifestyles in elderly colorectal cancer patients, which may help prevent frailty.
Journal
IF:
2.7
Papers: 436
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Citations: 4.6K
Researchers
M
Mengjiao Zhong
H-index:
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Papers: 1
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Citations: 0
X
Xiaodan Wu
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Papers: 1
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Citations: 0
X
Xinxin Li
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Papers: 1
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Citations: 0
J
Jingyue Xie
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0
Papers: 1
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Citations: 0
X
Xiaoxuan Wang
H-index:
0
Papers: 1
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Citations: 0
View moreOrganization
C
Collaborative Innovation Center for Cancer Medicine
Scholars:
349
Papers: 100
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Citations: 0
S
Sun Yat-sen University
Scholars:
3.7K
Papers: 1.1K
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Citations: 1.6W
Cited Papers