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Memory, Sleep, and Tau Function

delete2023-07-18
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PRE
AI
J
Jesús Ávila *
G
George Perry
DOI:10.3233/JAD-230230delete
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Abstract

Abstract

En 中文
Memory consolidation related to the hippocampal-cortex connection takes place during sleep. This connection may involve at least two steps-one in the NREM phase of sleep (transmission) and the other in the REM phase (consolidation). In this brief report, we comment on the role of tau protein in these two phases of sleep. The absence of tau decreases d waves in NREM, whereas the overexpression of modified (phosphorylated and/or mutated) tau alters theta waves in REM.
Keywords:
Alzheimer's disease
delta waves
memory
NREM phase
sleep
tau

Journal

Journal of Alzheimer's Disease cover
Journal of Alzheimer's Disease
IF:
3.1
Papers:
1.1W
Citations:
3.7W

Organization

C
consejo superior de investigaciones cientificas (csic)
Scholars:
8.8W
Papers: 8.5W
Citations: 125
C
csic - centro de biologia molecular severo ochoa (cbm)
Scholars:
1.3K
Papers: 828
Citations: 1