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Menin in normal and malignant megakaryopoiesis
J
S
DOI:10.1016/j.ccell.2026.06.012.png)
Abstract
En 中文
Severe thrombocytopenia is a known complication of menin inhibitor therapy; however, the mechanism underlying this effect is unknown. In this issue of Cancer Cell, Wen et al. demonstrate that menin is a key component of normal megakaryopoiesis and establish menin as a therapeutic vulnerability in myeloproliferative neoplasms.
Journal
IF:
44.5
Papers:
413
Citations:
5.6W
