1
Return

Menin in normal and malignant megakaryopoiesis

delete2026-07-09
delete0
PRE
AI
J
Justin C. Wheat
S
Sheng F. Cai *
DOI:10.1016/j.ccell.2026.06.012delete
deleteOriginal
deleteOriginal request for help
deleteShare
deleteSave
Abstract

Abstract

En 中文
Severe thrombocytopenia is a known complication of menin inhibitor therapy; however, the mechanism underlying this effect is unknown. In this issue of Cancer Cell, Wen et al. demonstrate that menin is a key component of normal megakaryopoiesis and establish menin as a therapeutic vulnerability in myeloproliferative neoplasms.

Journal

Cancer Cell cover
Cancer Cell
IF:
44.5
Papers:
413
Citations:
5.6W

Organization

M
memorial sloan kettering cancer center
Scholars:
2.3K
Papers: 660
Citations: 1
Cited Papers

Cited Papers

Citing Papers

Citing Papers