Metabolic and psychiatric changes after laparoscopic sleeve gastrectomy in patients with mood disorders and metabolic syndrome

2026-06-25

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Shuaichen Li

Fengying Tan

Jinglan Tan

Yanwei Guo

Qiuyan Li

Dan Li *

DOI：10.1016/j.jpsychores.2026.112909

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• LSG was associated with marked metabolic improvement at 12 months. • Depressive symptom burden decreased during follow-up. • Psychiatric worsening often followed non-prescribed psychotropic discontinuation. • Close multidisciplinary follow-up is important after bariatric surgery.

Metabolic and psychiatric changes after laparoscopic sleeve gastrectomy in patients with mood disorders and metabolic syndrome

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