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Methods and Instrumentation for Quantitative Analysis with Immunoplasmonic Nanoprobes
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DOI：10.1016/j.snb.2025.139010.png)
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Abstract
En 中文
Immunoplasmonic nanoprobes represent a novel class of diagnostic labels designed to advance quantitative biosensing and analysis. By combining the unique optical properties of plasmonic nanoparticles with selective biomolecular recognition, they enable highly sensitive, multiplexed, and quantitative detection of disease biomarkers. This article highlights key requirements for their development, including nanoparticle fabrication, bioconjugation, and methods for optical detection and digital analysis. We also present experimental approaches and instrumentation that facilitate their application in cytopathology and histopathology. Together, these tools establish a foundation for next-generation biosensing platforms capable of delivering precise, automated diagnostic insights with broad implications for clinical diagnostics and biomedical research.
Keywords:
metallic nanoparticles
analytical plasmonic nanoprobes
biosensing
dark-field microscopy
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Citations:
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