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Microbial valorization of lignin to malic acid by Aspergillus niger
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DOI：10.1016/j.biortech.2026.134018.png)
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Abstract
En 中文
• Engineered Aspergillus niger converts lignin-derived aromatics to malic acid. • Overexpression of C4 dicarboxylate transporter enhances malic acid secretion. • Medium optimization enhances fungal conversion and production stability. • Demonstrates first direct fungal conversion of real lignin streams to malic acid.
Keywords:
Lignin valorization
Transporter engineering
Aromatic bioconversion
Dicarboxylic acid production
Fungal biotechnology
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