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Microfluidic-based electrically driven particle manipulation techniques for biomedical applications

delete2025-01-01
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王久林 cover
王久林 (Jiulin Wang)
X
Xinyuan Cui
W
Wei Wang
Z
Zhang, Quili
G
Guo, Xiaonan
L
Liang, Yanfeng
L
Lin, Shujin
B
Bingfeng Chu *
DOI：10.1039/d4ra05571cdelete
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Abstract

Abstract

En 中文
Microfluidic chips exhibit unique advantages in both economy and rapidity, particularly for the separation and detection of biomolecules. In this review, we first introduced the mechanisms of several electrically driven methods, such as electrophoresis, dielectrophoresis, electro-wetting and electro-rotation. We then discussed in detail the application of these methods in nucleic acid analysis, protein manipulation and cell treatment. In addition, we outlined the considerations for material selection, manufacturing processes and structural design of microfluidic chips based on electrically driven mechanisms.
Keywords:
INSULATOR-BASED DIELECTROPHORESIS
ON-A-CHIP
ELECTROWETTING-BASED ACTUATION
FREE-FLOW ELECTROPHORESIS
DIELECTRIC-PROPERTIES
CAPILLARY-ELECTROPHORESIS
MICROCHIP ELECTROPHORESIS
ZONE-ELECTROPHORESIS
SINGLE-CELL
ELECTRODELESS DIELECTROPHORESIS

Journal

RSC Advances cover
RSC Advances
IF:
4.6
Papers:
7.7K
Citations:
20.9W

Organization

No organization information available