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Milk fat globule membrane-supplemented infant formula modulates Bifidobacterium longum subsp. infantis exopolysaccharide production and supports goblet cell barrier homeostasis

delete2026-06-16
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C
Celeste Miller
R
Rafael Jiménez-Flores *
DOI:10.1016/j.jff.2026.107388delete
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Abstract

Abstract

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• Digested IF with MFGM added to B. infantis growth media increases EPS production. • B. infantis supernatant applied to goblet cells allows for mucosal barrier integrity. • Relative TEER homeostasis observed with B. infantis supernatant. • B. infantis supernatant treatment results in MUC5AC and TFF3 expression homeostasis.
Keywords:
Milk fat globule membrane
Exopolysaccharides
Bifidobacterium infantis
Intestinal barrier
Goblet cells
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Journal of Functional Foods cover
Journal of Functional Foods
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