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Missing Outcome Data in Epidemiologic Studies

delete2022-10-12
delete15
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OA
AI
S
Stephen R. Cole *
P
Paul N. Zivich
J
Jessie K. Edwards
R
Rachael K. Ross
B
Bonnie E. Shook‐Sa
J
Joan T. Price
J
Jeffrey S. A. Stringer
DOI:10.1093/aje/kwac179delete
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Abstract

Abstract

En 中文
Missing data are pandemic and a central problem for epidemiology. Missing data reduce precision and can cause notable bias. There remain too few simple published examples detailing types of missing data and illustrating their possible impact on results. Here we take an example randomized trial that was not subject to missing data and induce missing data to illustrate 4 scenarios in which outcomes are 1) missing completely at random, 2) missing at random with positivity, 3) missing at random without positivity, and 4) missing not at random. We demonstrate that accounting for missing data is generally a better strategy than ignoring missing data, which unfortunately remains a standard approach in epidemiology.
Keywords:
bias
error
generalized computation
imputation
missing data
precision

Journal

American Journal of Epidemiology cover
American Journal of Epidemiology
IF:
4.8
Papers:
9.9K
Citations:
3.7W

Organization

U
university of north carolina
Scholars:
7.4W
Papers: 6.5W
Citations: 93
U
University of North Carolina School of Medicine
Scholars:
1.6W
Papers: 1.1W
Citations: 20
U
University of North Carolina Chapel Hill
Scholars:
3.9W
Papers: 3.1W
Citations: 46
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