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Mitochondrial alterations associated with zeolitic imidazolate framework-8 nanoparticle-induced reproductive toxicity in earthworms
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DOI：10.1016/j.ecoenv.2026.120608.png)
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Abstract
En 中文
• ZIF-8 exhibits formulation-dependent toxicity to earthworms, with methanol-dispersed particles showing the lowest LC50 value. • ZIF-8 induces severe reproductive damage, including clitellar atrophy and germinal epithelial degeneration. • Mitochondrial ultrastructural disruption is associated with ZIF-8-induced reproductive toxicity. • Formulation characteristics and mitochondrial toxicity are critical for nanomaterial environmental risk assessment.
Keywords:
Zeolitic imidazolate framework-8 nanoparticles
Earthworm
Toxicity assessment
Mitochondrial damage
Journal
E
IF:
6.1
Papers:
1.8W
Citations:
6.9W
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Cited Papers