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Modeling HFpEF in animals

delete2025-11-28
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PRE
AI
D
David A. Kass *
DOI:10.1038/s44161-025-00754-7delete
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Abstract

Abstract

En 中文
There is great interest in modeling human HFpEF in animals to identify underlying mechanisms and ultimately improve sorely needed therapies. Our current models are a step forward but still fall short in several crucial ways, particularly by not capturing the severity of heart failure features common in patients.
Keywords:
HFpEF
animal models
heart failure
disease modeling
therapeutic development

Journal

N
Nature Cardiovascular Research
IF:
10.8
Papers:
143
Citations:
0

Organization

J
Johns Hopkins University School of Medicine
Scholars:
2.1K
Papers: 748
Citations: 2