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Abstract
En 中文
The folding of RNA sequences into secondary structures is a simple yet biophysically grounded model of a genotype-phenotype map. Its computational and mathematical analysis has uncovered a surprisingly rich statistical structure characterized by shape space covering, neutral networks and plastogenetic congruence. I review these concepts and discuss their evolutionary implications. (C) 2002 Wiley Periodicals, Inc.
Keywords:
SEQUENCE STRUCTURE MAPS
SECONDARY STRUCTURES
NEUTRAL NETWORKS
EXHAUSTIVE ENUMERATION
STRUCTURE PREDICTION
EVOLUTION
SPACE
LANDSCAPES
STABILITY
SELECTION
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