.png){kind=icon}
.png){kind=icon}
Return
Modified β-glucans promote saponin and fucosylated chondroitin sulfate biosynthesis in sea cucumber Apostichopus japonicus in association with activation of the TLR-MAPK signaling pathway
.png){kind=icon}
PRE
AI
Z
Z
W
H
J
Y
M
W
S
M
N
DOI：10.1016/j.fsi.2026.111632.png)
.png){kind=icon}
Original request for help.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• Modified β-glucans increase saponin and FCS accumulation in A. japonicus. • Modified β-glucans up-regulate saponin and FCS biosynthesis genes. • Modified β-glucans up-regulate TLR-MAPK axis genes and MAPK (p38/ERK) proteins. • MAPK blockade reduces β-glucan-induced saponin and FCS accumulation. • TLR-MAPK axis associates immune responses with saponin and FCS accumulation.
Keywords:
Aquatic product quality
Bioactive compounds
Immune-metabolic crosstalk
Mevalonate pathway
Chondroitin biosynthesis pathway