Molecular and functional characterization of interleukin-1β in red drum (Sciaenops ocellatus) and its pivotal role in antibacterial immunity

2025-12-15

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Lin Zhang

Jinglu Ma

Jingyao Yu

DOI：10.1016/j.fsi.2025.111076

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• Homologue of IL-1β was identified from red drum, Sciaenops ocellatus. • SoIL-1β and SoIL-1RI were upregulated after Gram-negative bacteria infection both in vitro and in vivo. • SoIL-1β could activate the NF-κB signaling pathway. • SoIL-1β was participated in regulating the antibacterial immune response.

Molecular and functional characterization of interleukin-1β in red drum (Sciaenops ocellatus) and its pivotal role in antibacterial immunity

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