Molecular and toxicological study of the plasticizers exposure-induced metabolic disorders

doi:10.1016/j.envpol.2026.127910

Molecular and toxicological study of the plasticizers exposure-induced metabolic disorders

2026-03-03

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DOI：10.1016/j.envpol.2026.127910

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• Network toxicology reveals molecular links between PAEs and metabolic diseases. • Evidence integration uncovers PAEs-induced metabolic disorder mechanisms. • GSK3B, CASP3 and insulin-related pathways emerge as central targets of PAEs. • AlphaFold with docking validates PAEs-protein interaction mechanisms.

Molecular and toxicological study of the plasticizers exposure-induced metabolic disorders

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