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Molecular Classification of Resected Primary Duodenal Adenocarcinoma

delete2025-07-11
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J
Jacob de Bakker *
H
Hedde D. Biesma
T
Tanya T.D. Soeratram
J
Jacqueline Egthuijsen
T
Tim de Back
M
Marc G. Besselink
V
Vermeulen, Louis
B
Bauke Ylstra
N
Nicole van Grieken *
DOI:10.1002/gcc.70061delete
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Abstract

Abstract

En 中文
The molecular and histological characteristics of primary duodenal adenocarcinoma (DA) have been poorly described, which hampers the development of new treatment options. This study aimed to characterize the landscape of chromosomal copy number aberrations (CNAs), microsatellite instability status, and tumor–stroma content, and their association with clinicopathological characteristics of patients with DA.
Keywords:
copy number aberrations
digital image analysis
duodenum adenocarcinoma
microsatellite instability
molecular subgroups
tumor–stroma
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Journal

Genes Chromosomes and Cancer cover
Genes Chromosomes and Cancer
IF:
2.8
Papers:
3.3K
Citations:
4.7K

Organization

C
Cancer Center Amsterdam
Scholars:
274
Papers: 124
Citations: 1.3K
D
Department of Surgery
Scholars:
4.1K
Papers: 1.7K
Citations: 2
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