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Molecular surveillance of penicillinase-producing Neisseria gonorrhoeae to inform empiric treatment in remote settings: experience over 12 years
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DOI:10.1093/jac/dkag197.png)
Abstract
En 中文
The remote regions of Western Australia (WA) have high gonorrhoea notification rates but low Neisseria gonorrhoeae penicillin resistance permitting the use of empiric combination oral amoxicillin, azithromycin and probenecid therapy. The predominance of molecular-based gonorrhoea diagnoses and consequent reduced phenotypic susceptibility data required PCR-based N. gonorrhoeae penicillin resistance surveillance to ensure the ongoing reliability of oral penicillin-based therapy for uncomplicated gonorrhoea in this setting.
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