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Multi-omics-guided targeting of the CD14–NF-κB axis with PGA1-loaded liposomes restores CD14hi TSPCs function and promotes tendon–bone healing in diabetes
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DOI：10.1016/j.mtbio.2026.103509.png)
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Abstract
En 中文
Type 2 diabetes mellitus (T2DM) is common in patients with rotator cuff tears (RCTs) and is associated with poor tendon–bone healing and high retear rates. Tendon stem/progenitor cells (TSPCs) are central to tendon–bone integration, but how T2DM reprograms TSPCs and whether this can be reversed remain unclear.
Keywords:
CD14
PGA1
TSPCs
Diabetes
Tendon–bone healing
Rotator cuff tear
Liposomes
Multi-omics
Journal
IF:
10.2
Papers:
3.6K
Citations:
9.5K
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