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Multi-system toxicity of lead (Pb) in Procambarus clarkii: Integrated analysis of tissue damage, immune dysfunction, oxidative stress, and microbial dysbiosis via multi-omics approaches

delete2025-08-27
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PRE
AI
L
Lang Zhang
Z
Ziwei Song
Q
Qiuying Qin
L
Li He
田娟 (Juan Tian)
Y
Yali Yu
Y
Yingchun Mu
L
Liqi Zhong
Z
Zongbin Cui *
J
Jinhua Gan *
DOI:10.1016/j.cbpc.2025.110331delete
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Abstract

Abstract

En 中文
• Pb caused structural damage of the hepatopancreas and intestines. • Pb induced the hepatopancreatic transcriptome changes of P. clarkii. • Pb influenced the intestinal microbiota of P. clarkii. • DEGs related to immune defense, oxidation-reduction, etc. were identified.
Keywords:
lead
hepatopancreas
intestine
transcriptome
microbiota

Journal

C
Comparative Biochemistry and Physiology C-Toxicology and Pharmacology
IF:
4.3
Papers:
3.7K
Citations:
8.8K

Organization

H
harbin institute of technology
Scholars:
8.0W
Papers: 6.6W
Citations: 66
M
Ministry of Agriculture and Rural Affairs
Scholars:
3.2K
Papers: 980
Citations: 4.1W
G
Guangdong Academy of Sciences
Scholars:
6.3K
Papers: 4.7K
Citations: 7.7K
C
Chinese Academy of Fishery Sciences
Scholars:
8.6K
Papers: 4.6K
Citations: 5.6K
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