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Multifocal multiphoton endoscope
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DOI：10.1364/OL.37.001349.png)
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Abstract
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We report a miniaturized resonant/non-resonant multi-fiber raster scanner that is paired with a gradient-index lens assembly to achieve a compact and flexible multifocal multiphoton endoscope capable of longitudinal parallel image acquisition. Multiphoton images are obtained simultaneously at three axial depths, separated by >= 4.8 mu m, by incorporating three axially offset double clad optical fibers into the miniaturized scanner. The fabricated endoscope has an outer diameter of 3 mm, a rigid length of 4 cm, and acquires images at 4 frames/s per focal plane, with lateral and axial resolutions for two-photon imaging of 0.8 and 10 mu m, respectively. (C) 2012 Optical Society of America
Keywords:
2-PHOTON MICROSCOPE
FLUORESCENCE
COMPACT
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