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N-acetylcysteine for non-paracetamol-induced acute liver failure in children: A systematic review and meta-analysis

delete2026-07-03
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OA
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A
Alise D. E. de Groot
D
Désanka M. Stoppels
A
Arno R. Bourgonje
W
Willemien F. J. Hof
M
Martin C. J. Kneyber
D
Daan J. Touw
H
Henkjan J. Verkade
P
Paola Mian *
DOI:10.1002/bcp.70680delete
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Abstract

Abstract

En 中文
Non-surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N-acetylcysteine (NAC) is proven effective in paracetamol-induced ALF, its potential benefits in non-paracetamol ALF for paediatric patients remain unclear. This systematic review aimed to evaluate the efficacy of NAC in paediatric patients with non-paracetamol-induced ALF.
Keywords:
acute liver failure
N-acetylcysteine
non-paracetamol-induced acute liver failure
paediatrics
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Journal

British Journal of Clinical Pharmacology cover
British Journal of Clinical Pharmacology
IF:
3
Papers:
8.5K
Citations:
1.8W

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U
university of groningen
Scholars:
4.7K
Papers: 2.0K
Citations: 0
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