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Nanocapsules as Smart Natural Product Drug Delivery Systems: Recent Advances and Future Directions
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DOI：10.1039/D6NH00103C.png)
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Abstract
En 中文
In the field of biotechnology and pharmaceuticals; bioactive compounds play vital roles as fortifying ingredients and drug components. As these products are naturally acquired from plant resources; their stability and functionality have to be preserved essentially. Of late; these bioactive components are effectively preserved as capsules through the process of nanoencapsulation; which has been reported to successfully maintain their shelf life and structures and prolong their functional ability. Here; the authors had attempted to elaborate reported studies on the materials used in the fabrication of nanocapsules; several modes of nanoencapsulation; the analytical methods to assess the characteristics of nanocapsules; and the natural product bioactives that are encapsulated; and their utilisation in various pharmacological applications. The article significantly discussed how these nanocapsules are remarkable in targeted drug delivery and sustained drug release. The present review throws a limelight on the challenges that were faced during their production and commercialisation. In addition; current strategies to overcome the disadvantages in the process were also emphasised. Overall; this review article will substantially serve as a comprehensive resource to understand nanoencapsulation and implement it with stateof-the-art technologies to enhance the nutritive; mechanical; and functional properties of the bioactive compounds for consumption and biomedical applications.
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