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Nanoparticle aggregation logic computing controlled by DNA branch migration
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DOI：10.1063/1.4819840.png)
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Abstract
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In this work, nanoparticle aggregation is utilized to establish a nanoparticle computing system, and the computing process is triggered by adding specific DNA signals. Through DNA strand displacement, cascading regulations of aggregations are implemented. The logic computing operations of OR and OR-AND are realized by a color change, resulting from the aggregations induced by DNA self-assembly. All reactions are performed under room temperature and without changing ion strength in buffers. By analysis of the color, the computing results can be detected through naked eyes. In addition, the aggregation structures are distinctly demonstrated by transmission electron microscopy. (C) 2013 AIP Publishing LLC.
Keywords:
GOLD
COMPUTATION
CIRCUITS
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