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Nanoparticle Contrast Agents for Photon-Counting Computed Tomography: Recent Developments and Future Opportunities
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DOI：10.1002/wnan.70004.png)
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Abstract
En 中文
The clinical availability of photon-counting computed tomography (PCCT) has ushered in a new era of CT imaging. Spectral imaging coupled with superior contrast resolution, and ultrahigh spatial resolution (200 mu m) offered by PCCT has the potential to revolutionize value-driven imaging. The potential of multicolor PCCT has generated excitement, and renewed interest, in novel contrast agent development for comprehensive disease interrogation, prediction and monitoring of treatment outcomes. Nanoparticles provide a versatile and powerful platform for the development of next generation contrast agents for spectral PCCT. In this article, we review recent developments and use of nanoparticle contrast agents for PCCT. We also discuss future research and translational opportunities for nanoparticle-based CT contrast agents enabled by the advent of PCCT and describe key considerations for their clinical translation.
Keywords:
cellular imaging
cellular tracking
computed tomography
molecular imaging
nanoparticle contrast agent
photon-counting CT
radiomics
spectral CT
theranostics
Journal
IF:
8.2
Papers:
924
Citations:
5.7K
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