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NAT10 promotes lung cancer progression by enhancing glutamine metabolism through increasing ac4C modification on NIT2

delete2026-04-23
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PRE
AI
D
Dafu Yang
Y
Yue Zhu
Y
Yang Liu
Z
Zhaoxia Dai *
DOI：10.1016/j.molimm.2026.04.010delete
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Abstract

Abstract

En 中文
• NAT10 is high expressed in lung cancer. • NIT2 overexpression restores tumor growth inhibited by remodelin. • NAT10 increases the ac4C modification and the stability of NIT2 mRNA in lung cancer cells.
Keywords:
NAT10
lung cancer
ac4C modification
NIT2
glutamine metabolism

Journal

Molecular Immunology cover
Molecular Immunology
IF:
3
Papers:
9.3K
Citations:
1.3W

Organization

No organization information available