Network pharmacology and in vitro exploration of the antiglioma mechanism of anthocyanins from Lycium ruthenicum Murr

Hongwei Zhou

doi:10.1016/j.gene.2026.150277

Network pharmacology and in vitro exploration of the antiglioma mechanism of anthocyanins from Lycium ruthenicum Murr

2026-06-18

0

PRE

AI

H

Hongwei Zhou

J

Jinwen Sima *

S

Shenglei Wang

S

Shijia Lu

J

Jialin Liang

X

Xinyao Li

T

Tiantian Lian

C

Congcong Wang

DOI：10.1016/j.gene.2026.150277

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Abstract

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Lycium ruthenicum Murr (black goji berry) is a traditional edible ethnomedicine in Northwest China, valued for metabolic regulation. Building on the ethnopharmacological background of L. ruthenicum, the research employed network pharmacology, in vitro assays, and molecular docking to explore the inhibitory effects of L. ruthenicum anthocyanins (LRA) on human glioma cells and to elucidate their potential molecular mechanisms.

Network pharmacology and in vitro exploration of the antiglioma mechanism of anthocyanins from Lycium ruthenicum Murr

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