.png){kind=icon}
.png){kind=icon}
Return
Network Toxicology, Molecular Docking, and Molecular Dynamics to Explore the Epilepsy Mechanism Induced by Tetramine Poisoning
.png){kind=icon}
OA
AI
M
H
Y
S
Y
X
C
DOI：10.1016/j.brainresbull.2026.111915.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
• Tetramine poisoning frequently leads to epilepsy, which has complex mechanisms and poor treatment outcomes. • This study identified HIF1A, HSP90AB1, MMP9, SRC, and STAT3 as core targets regulating tetramine-induced epilepsy. • The HIF-1, PI3K-Akt, Ras, Toll-like receptor, chemokine, and neurotrophin signaling pathways appear to be critical in the regulation of tetramine-induced epilepsy. • Network toxicology methods have indicated that tetramine may induce epilepsy through multiple targets and signaling pathways.
Keywords:
Tetramine poisoning
Epilepsy
Network toxicology
Molecular docking
Targets
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
3.7
Papers:
6.8K
Citations:
1.2W
Organization
Cited Papers