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Neuron-Derived Neuroinflammation in Neurodegenerative Diseases: Mechanisms and Intervention Prospects
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DOI：10.1016/j.phrs.2026.108383.png)
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Abstract
En 中文
• Break the notion that neurons are only passive inflammation victims and propose neurons as one of the key active regulators. • Decipher immune heterogeneity of vulnerable neurons across NDDs, enabling precise targeting of neuronal subtypes. • Transitioning from traditional targeted peripheral/glial therapy to neuron-targeted immunotherapy.
Keywords:
Neurodegenerative diseases
Neuron-derived
Neuroinflammation
Mechanisms
Intervention Prospects
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