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Neuronal differentiation of neuroblastoma cell lines for neurological disease modeling
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DOI：10.1016/j.isci.2026.116469.png)
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Abstract
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• Transcription factor activity inference with RNA-seq classifies ADRN- and MES-type • Synaptophysin serves as an ADRN-type marker and neuronal differentiation marker • Selected ADRN-type lines can form neuron-like cells by differentiation treatment • Differentiated neuron-like cells express several neurotransmitter pathway genes
Keywords:
Neuroscience
Molecular neuroscience
Transcriptomics
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