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Neurotensin-mediated modulation of CYP19A1 and estrogen homeostasis during inflammation: an integrated network pharmacology, molecular docking and in vivo investigation

delete2026-06-19
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PRE
AI
S
Sonia Srivastava
B
Banalata Mohanty *
DOI：10.1016/j.intimp.2026.117046delete
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Abstract

Abstract

En 中文
• Neurotensin regulates inflammatory–steroidogenic crosstalk during inflammation. • NTSR1-dependent mechanism safeguards the steroidogenic pathways against inflammatory insults. • This study employed a combination of network pharmacology, molecular docking, and experimental validation.

Journal

International Immunopharmacology cover
International Immunopharmacology
IF:
4.7
Papers:
1.6W
Citations:
4.1W

Organization

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