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New dimensions for fluorescence-based barcoding in complex mixtures
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DOI：10.1038/s41565-024-01686-2.png)
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Abstract
En 中文
Combining single-molecule F & ouml;rster resonance energy transfer (FRET) and fluorescence lifetime information inside an anti-Brownian electrokinetic (ABEL) trap makes it possible to distinguish dozens of biomolecules in a sample mixture. This method enables extensive barcoding of biomolecules with a minimal set of chemical components and opens up a path toward biomolecule quantification in complex mixtures.