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Null models for lesion network mapping
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DOI：10.1038/s41593-026-02259-3.png)
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Abstract
En 中文
Van den Heuvel et al. show that lesion-network mapping (LNM)-derived circuits converge across disorders and argue that this convergence reflects a fundamental methodological limitation of LNM. We evaluate ways forward for future LNM studies, including robust null models, in light of these concerns. We view recapitulation of connectome modularity and high-order network properties by LNM as clinically informative and biologically meaningful.
Keywords:
Network models
Neural circuits
Biomedicine
general
Neurosciences
Behavioral Sciences
Biological Techniques
Neurobiology
Animal Genetics and Genomics