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Occupational dust exposure is associated with cardiovascular risk via glycerophospholipid metabolism and IL-6-mediated endothelial inflammation: Insights from multi-omics integration
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DOI：10.1016/j.envpol.2026.128816.png)
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Abstract
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• CDE was associated with increased cardiovascular risk metrics. • CDE may impact cardiovascular risk metrics via disruption of lipid homeostasis. • Glycerophospholipid metabolism and insulin resistance may mediate CDE-risk link. • Multi-omics evidence shows IL-6 links metabolic disorder to endothelial inflammation. • Serum IL-6 levels positively correlated with CDE in coal miners.
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