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Oleoyl-hyaluronate nanoparticles for enhanced stability and bioactivity of encapsulated coenzyme Q10
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DOI:10.1016/j.ijpharm.2026.126958.png)
Abstract
En 中文
This study presents the successful encapsulation of coenzyme Q10 (CoQ10) within sodium oleoyl hyaluronate (O-HA; Mw ∼12,000 Da) nanoparticles, creating a concentrated, liquid colloidal dispersion. The nanoprecipitation process achieved high encapsulation efficiency (up to 96%) and a loading capacity of 2.4–3.0 mg·mL−1.
Keywords:
Coenzyme Q10
Sodium oleoyl hyaluronate
Nanoparticles
Encapsulation efficiency
Bioactivity
Journal
IF:
5.2
Papers:
2.2W
Citations:
6.7W
