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Onconephrology
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DOI：10.1016/j.ccc.2020.11.004.png)
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Abstract
En 中文
? Acute kidney injury is common in patients with cancer. ? Patients with cancer who are critically ill have the highest risk of acute kidney injury. ? Acute kidney injury is associated with increased morbidity, mortality, length of stay, and costs in hospitalized patients with cancer. ? Patients with malignancy can develop kidney diseases similar to other acutely and chronically ill patients and are also at risk for unique kidney syndromes because of either the cancer itself or its treatment. ? It is important for nephrologists to have knowledge about newer chemotherapeutics and understand the pathophysiology of the renal injury caused by them, which will help guide ican Cancer Society, Cancer Facts & Figures 2020 Annual report, more than 1.8 million new cancer cases are expected to be diagnosed in 2020. About 606,520 Americans are expected to die of cancer in 2020, which translates to about 1660 deaths per day. Cancer is the second most common cause of death in the United States, exceeded only by heart disease. Acute kidney injury (AKI) is common in patient with cancer1 .2 Nearly 80% of patients who were studied in the BIRMA study received nephrotoxic medications and were in need of dose adjustments.1 The development of AKI can further limit cancer treatment options, increase toxicity to chemotherapeutics, reduce drug delivery, exclude patients from potential clinical trials, and exclude them from eligibility for hematopoietic
Keywords:
Acute kidney injury in cancer
Tumor lysis syndrome
Cast nephropathy
CAR-T cell therapy
Chemotherapy induced kidney injury
Cancer related thrombotic microangiopathy
Sinusoidal occlusion syndrome
Hematopoietic stem cell transplantation induced kidney injury
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