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One-pot synthesis of laurolactam from cyclododecene and air
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DOI：10.1039/D5CY01180A.png)
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Abstract
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Laurolactam is an essential compound for the synthesis of polyamides and requires four separated steps for its industrial production; starting from cyclododecane. Here we show a one-pot synthesis of laurolactam from cyclododecene; without intermediate purifications; in 66% yield. If desired; the intermediate cyclododecanone oxime can also be isolated; and the procedure is applicable for the production of caprylolactam.
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