.png){kind=icon}
.png){kind=icon}
Return
Open-Source, Python-Based Redevelopment of the ChemShell Multiscale QM/MM Environment
.png){kind=icon}
OA
AI
DOI：10.1021/acs.jctc.8b01036.png)
.png){kind=icon}
.png){kind=icon}
Share.png){kind=icon}
Save
Abstract
En 中文
ChemShell is a scriptable computational chemistry environment with an emphasis on multiscale simulation of complex systems using combined quantum mechanical and molecular mechanical (QM/MM) methods. Motivated by a scientific need to efficiently and accurately model chemical reactions on surfaces and within microporous solids on massively parallel computing systems, we present a major redevelopment of the ChemShell code, which provides a modern platform for advanced QM/MM embedding models. The new version of ChemShell has been re-engineered from the ground up with a new QM/MM driver module, an improved parallelization framework, new interfaces to high performance QM and MM programs, and a user interface written in the Python programming language. The redeveloped package is capable of performing QM/MM calculations on systems of significantly increased size, which we illustrate with benchmarks on zirconium dioxide nanoparticles of over 160000 atoms.
Keywords:
QUANTUM MECHANICS/MOLECULAR MECHANICS
FINDING SADDLE-POINTS
ELASTIC BAND METHOD
MOLECULAR-DYNAMICS
HALOGENASE SYRB2
INSIGHTS
PROTEIN
REACTIVITY
SIMULATIONS
SUBSTRATE
AI Summary
Key information extracted from the uploaded paper, including a brief overview, abstract, background, key highlights, visual analysis, and future outlook.
Journal
IF:
5.5
Papers:
1.1W
Citations:
5.4W