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Optically and Structurally Stabilized Plasmo-Bio Interlinking Networks
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DOI：10.1002/admi.202001370.png)
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Abstract
En 中文
Visualization of dynamic interlinking networks which respond and adapt to the constantly changing environment would be highly beneficial in developing new composite materials and active/responsive materials. Here, optically and structurally stabilized plasmo-bio interlinking networks (PBINs) free from photobleaching for high resolution, long term visualization are reported. Necessary for structural and optical stability, a new stability algorithm to comprehensively quantify stability and detect minute instability undetectable by traditional methods is introduced. Biocompatible plasmonic gold nanorods (Bio-AuNRs) are synthesized for high resolution, long term imaging by utilizing bromide-free alternatives to achieve CTA+ free. Systematic physical, chemical, and biological characterizations reveal the structural and optical stability of Bio-AuNRs required for constructing PBIN. Lastly, with actin as a model of interlinking networks of the cytoskeleton, optically and structurally stable PBIN (100% CTA+ free, 97% crosslinking rate) in applications as active/responsive materials, are demonstrated.
Keywords:
actin
plasmonic nanostructures
responsive materials
subdiffraction
super‐ resolution
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