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Optimized Gradient Waveforms for Tensor-Valued Diffusion MRI Under Time-Dependent Diffusion Using Double-Isotropic Matched Encoding (DIME)

delete2026-09-29
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OA
AI
F
Felix Mortensen *
V
Viktor Olsson
A
Athanasios Grigoriou
S
Samo Lasič
M
Malwina Molendowska
R
Ronnie Wirestam
F
Filip Szczepankiewicz
DOI:10.1002/mrm.70602delete
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Abstract

Abstract

En 中文
Spherical and linear b-tensor encoding (STE and LTE) enables quantification of microscopic diffusion anisotropy and diffusional variance. However, such waveforms are often variably sensitive to time-dependent diffusion, causing rotational variance and spectral mismatch. We propose double-isotropic matched encoding (DIME), which enforces isotropy in diffusion- and restriction-weighting tensors ( and ) and STE/LTE pairs matched in restriction sensitivity.
Keywords:
concomitant fields
diffusion acquisition
experimental design
microstructure
nerve stimulation
time-dependent diffusion MRI

Journal

Magnetic Resonance in Medicine cover
Magnetic Resonance in Medicine
IF:
3
Papers:
1.2W
Citations:
3.1W

Organization

L
Lund University
Scholars:
671
Papers: 267
Citations: 0
Cited Papers

Cited Papers

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errNing, Lipeng; Szczepankiewicz, Filip; Nilsson, Markus; Rathi, Yogesh; Westin, Carl-Fredrik
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Multidimensional diffusion MRI with spectrally modulated gradients reveals unprecedented microstructural detail
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errLundell, H.; Nilsson, M.; Dyrby, T. B.; Parker, G. J. M.; Cristinacce, P. L. Hubbard; Zhou, F-L; Topgaard, D.; Lasic, S.
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Histology-informed microstructural diffusion simulations for MRI cancer characterisation—the Histo-μSim framework
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errGrigoriou,Athanasios; Macarro,Carlos; Palombo,Marco; Navarro-Garcia,Daniel; Voronova,Anna Kira; Bernatowicz,Kinga; Barba,Ignasi; Escriche,Alba; Greco,Emanuela; Abad,María; Simonetti,Sara; Serna,Garazi; Mast,Richard; Merino,Xavier; Roson,Núria; Escobar,Manuel; Vieito,Maria; Nuciforo,Paolo; Toledo,Rodrigo; Garralda,Elena; Sala-Llonch,Roser; Fieremans,Els; Novikov,Dmitry S.; Perez-Lopez,Raquel; Grussu,Francesco
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Gradient waveform design for tensor-valued encoding in diffusion MRI
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errFilip Szczepankiewicz; Carl-Fredrik Westin; Markus Nilsson
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Concomitant gradient terms in phase contrast MR: Analysis and correction
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errBernstein, MA; Zhou, XHJ; Polzin, JA; King, KF; Ganin, A; Pelc, NJ; Glover, GH
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Concomitant Gradient Effects Across Field Strengths and Gradient Amplitudes: Improved Estimation of Errors and Correction of Concomitant Dephasing and Diffusion Weighting
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errOlsson,Viktor; Mortensen,Felix; Ljungberg,Emil; Testud,Frederik; Wirestam,Ronnie; Molendowska,Malwina; Szczepankiewicz,Filip
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