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Optimized-Unet: Novel Algorithm for Parapapillary Atrophy Segmentation

delete2021-10-13
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OA
AI
C
Cheng Wan
H
Han Li
Z
Zhipeng Yan
C
Chenghu Wang
Q
Qin Jiang
G
Guo-Fan Cao
许言午 cover
许言午 (Yanwu Xu) *
W
Weihua Yang *
DOI:10.3389/fnins.2021.758887delete
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Abstract

Abstract

En 中文
In recent years, an increasing number of people have myopia in China, especially the younger generation. Common myopia may develop into high myopia. High myopia causes visual impairment and blindness. Parapapillary atrophy (PPA) is a typical retinal pathology related to high myopia, which is also a basic clue for diagnosing high myopia. Therefore, accurate segmentation of the PPA is essential for high myopia diagnosis and treatment. In this study, we propose an optimized Unet (OT-Unet) to solve this important task. OT-Unet uses one of the pre-trained models: Visual Geometry Group (VGG), ResNet, and Res2Net, as a backbone and is combined with edge attention, parallel partial decoder, and reverse attention modules to improve the segmentation accuracy. In general, using the pre-trained models can improve the accuracy with fewer samples. The edge attention module extracts contour information, the parallel partial decoder module combines the multi-scale features, and the reverse attention module integrates high- and low-level features. We also propose an augmented loss function to increase the weight of complex pixels to enable the network to segment more complex lesion areas. Based on a dataset containing 360 images (Including 26 pictures provided by PALM), the proposed OT-Unet achieves a high AUC (Area Under Curve) of 0.9235, indicating a significant improvement over the original Unet (0.7917).
Keywords:
medical image segmentation
high myopia
parapapillary atrophy
convolutional neural network
fundus image
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Journal

Frontiers in Neuroscience cover
Frontiers in Neuroscience
IF:
3.2
Papers:
1.6W
Citations:
5.3W

Organization

N
Nanjing Medical University
Scholars:
4.7W
Papers: 2.8W
Citations: 3.5K
B
baidu
Scholars:
578
Papers: 471
Citations: 1