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Optimizing blister packaging design for solid-form pharmaceuticals

delete2025-08-25
delete0
PRE
AI
S
Seray Çakırgil
E
Eda Yücel *
DOI：10.1016/j.cie.2025.111478delete
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Abstract

Abstract

En 中文
• Optimization of blister packaging decisions in a Turkish pharmaceutical company. • Improve cost-effectiveness, carbon emission while preserving regulatory compliance. • Integrated problem of drug packing design, machinery investment, production planning. • A novel mixed-integer mathematical model and an ALNS-based metaheuristic are proposed. • Extensive computational experiments on realistic data sets.
Keywords:
blister packaging
optimization
pharmaceutical company
mixed-integer mathematical model
ALNS-based metaheuristic

Journal

Computers and Industrial Engineering cover
Computers and Industrial Engineering
IF:
6.5
Papers:
1.0W
Citations:
3.8W

Organization

No organization information available