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Organoid Imaging: Seeing Development and Function
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DOI：10.1146/annurev-cellbio-120320-035146.png)
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Abstract
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Organoids are miniaturized and simplified versions of an organ produced in vitro from stem or progenitor cells. They are used as a model system consisting of multiple cell types forming an architecture relevant to the organ and carrying out the function of the organ. They are a useful tool to study development, homeostasis, regeneration, and disease. The imaging of organoids has become a pivotal method to visualize and understand their self-organization, symmetry breaking, growth, differentiation, and function. In this review, we discuss imaging methods, how to analyze these images, and challenges in organoid research.
Keywords:
organoids
imaging
microscopy
live imaging
image analysis
Journal
IF:
11.4
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716
Citations:
9.9K
Organization
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