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Pan-cancer atlas of cellular architecture reveals a nearest-neighbour distance-associated biomechanical-immune axis involving CD4+ memory T cells

delete2026-07-30
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L
Linglong Huang *
A
Arne Östman
Y
Yunfan Sun
DOI:10.1002/ctm2.70742delete
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Abstract

Abstract

En 中文
The systematic link between cellular spatial organization and its biomechanical consequences remains a critical knowledge gap in human oncology.
Keywords:
CD4 memory T-cell
digital pathology
Hippo pathway
mechanical stress
multi-omics integration
nearest neighbour distance
spatial analysis
survival analysis
tumour microenvironment
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Journal

Clinical and Translational Medicine cover
Clinical and Translational Medicine
IF:
6.8
Papers:
2.6K
Citations:
9.6K

Organization

F
fudan university
Scholars:
11.3W
Papers: 7.6W
Citations: 121
K
karolinska institutet
Scholars:
6.1K
Papers: 2.3K
Citations: 0
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