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Parasitic infection and resource acquisition shape senescence through oxidative stress and energy depletion
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DOI：10.1093/evolut/qpag084.png)
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Abstract
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There is currently no theory which mechanistically links parasite virulence and host senescence. One driver of senescence is energy metabolism. We expect parasites to contribute to senescence because infection increases energy allocation to the immune system, which elevates oxidative stress and damages macromolecules. Additionally, parasites deplete their host’s energy, which can increase the host’s rate of mortality.
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