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Paratesticular Endometrial Stromal Sarcoma-Like Sarcoma With EPC1-SUZ12 Fusion
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DOI：10.1002/gcc.70052.png)
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Abstract
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Endometrial stromal sarcoma-like (ESS-like) sarcomas have rarely been described in male patients and represent a subset of Mullerian analog tumors. These ESS-like sarcomas most commonly arise in the paratesticular or pelvic regions and often harbor the same signature molecular fusion events that are typical of endometrial stromal sarcoma (ESS) of the uterine corpus. Here we report and describe an ESS-like sarcoma of the paratesticular soft tissue in an 85-year-old man with an EPC1-SUZ12 t(10;17)(p11.22;q12) fusion. This fusion event has been described in a high-grade uterine ESS one time previously where it displayed an aggressive clinical course. However, our patient showed no evidence of metastatic disease prior to surgery or in a short follow-up period after resection.
Keywords:
endometrial stromal sarcoma
EPC1-SUZ12
ESS-like sarcoma
male
paratesticular
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