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Pathogen evolution under strategy changes in vaccination campaigns: A game-theoretic framework
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DOI：10.1016/j.apm.2026.117225.png)
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Abstract
En 中文
• A multiscale framework that couples three interacting processes is proposed. • Heterogeneous updating rules could generate a Hopf bifurcation. • We observe the biological phenomenon of cryptic Red Queen dynamics. • High vaccine uptake can prevent the emergence of harmful variants. • Long-term evolution may favour specialist variants.
Keywords:
Pathogen evolution
Vaccination
Game-theoretic framework
Adaptation rates
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